Protecting Families against HIV/AIDS (PREFA) is a national Non-Governmental Organization (NGO) that was established in 2004,   under registration certificate number S.5914/4896 with a unique mandate to Champion comprehensive and evidence-based health and livelihood interventions, through a family-centered approach for the vulnerable and marginalized populations in Uganda. PREFA’s core Programs include: Maternal Newborn and child health (MNCH); Comprehensive HIV/AIDS services – including related non – communicable diseases; Adolescent and Youth Sexual and Reproductive Health services (AYSRH); Sustainable livelihood initiatives (SLIs); Orphaned and Vulnerable Children (OVC); Research & Advocacy and Capacity building. The programs are implemented through district and community led health systems strengthening approaches targeting adolescents, youth, women, children, families and key populations.